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You are here:Home » Antibodies » Abs to Apoptosis, Caspase » Anti -Caspase 1 (Caspase 1 Apoptosis-related Cysteine Peptidase, Caspase 1 Apoptosis-related Cysteine Protease, Caspase-1, CASP 1, CASP1, CASP-1, Interleukin 1 beta Convertase, IL1B Convertase, IL-1BC, IL1BC, Interleukin 1 beta Convertase Precursor, Interleukin

Anti -Caspase 1 (Caspase 1 Apoptosis-related Cysteine Peptidase, Caspase 1
Apoptosis-related Cysteine Protease, Caspase-1, CASP 1, CASP1, CASP-1, Interleukin 1 beta
Convertase, IL1B Convertase, IL-1BC, IL1BC, Interleukin 1 beta Convertase Precursor,
Interleukin

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B
Caspase 1 is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes that undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, p20 and p10, that dimerize to form the active enzyme. Caspase 1 was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in processes such as inflammation, septic shock, and wound healing. Caspase 1 has been shown to induce cell apoptosis and may function in various developmental stages (1).
Catalog #C2086-66Z
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-1:10,000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
IsotypeIgG
Clone No10J93
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH 7.2, 0.01% sodium azide, 0.05% BSA, 50% glycerol.
PuritySupernatant
ImmunogenSynthetic peptide corresponding to residues in human Caspase 1.
SpecificityRecognizes human Caspase 1 at ~45kD. Species Crossreactivity: mouse, rat
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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