Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to Apoptosis, Caspase » Anti -Caspase 2 (ICH-1, Nedd2)

Anti -Caspase 2 (ICH-1, Nedd2)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified E B
The caspase family of cystein proteases functions as fundamental effectors in apoptosis. These enzymes participate in a cascade that is triggered in response to proapoptotic signals and culminates in cleavage of a set of proteins, resulting in disassembly of the cell. Caspase-2, initially described as NEDD2/ICH1, was identified as a protein related to the Caenorhabditis elegans cell death protein CED-3 and mammalian interleukin-1beta-converting enzyme which is highly expressed in embryonic brain and down-regulated in adult brain.
Catalog #C2086-72J
ApplicationsSuitable for use in ELISA, Western Blotting. Other applications not tested.
Recommended DilutionWestern Blotting: 1:500-1:1000
Optimal dilutions to be determined by the researcher.
HybridomaDerived from hybridization of mouse SP2/O myeloma cells with spleen cells from BALB/c mice immunized with a recombinant human caspase-2 protein.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50?. Freeze at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No6j4
HostRat
SourceHuman
Concentration1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.1% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant human Caspase-2 (32-169aa) purified from E. coli
SpecificityRecognizes Caspase 2 (ICH-1, Nedd2)
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links