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You are here:Home » Antibodies » Abs to Apoptosis, Caspase » Anti -Caspase 2, NT (ICH-1, Nedd2, Caspase-2, CASP-2, Neural Precursor Cell Expressed Developmentally Down-regulated Protein 2, NEDD-2, Protease ICH-1, CASP2)

Anti -Caspase 2, NT (ICH-1, Nedd2, Caspase-2, CASP-2, Neural Precursor Cell Expressed
Developmentally Down-regulated Protein 2, NEDD-2, Protease ICH-1, CASP2)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IC IF
Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1b and IL-18. Although phylogenetically similar to this subfamily, Caspase-2 is thought to be involved in stress-induced apoptosis. Caspase-2 has two major isoforms; overexpression on the long form results in apoptosis while that of the short form suppresses cell death.
Catalog #C2086-72R
ApplicationsSuitable for use in Immunofluorescence, Western Blot and Immunocytochemistry. Other applications not tested.
Recommended DilutionImmunofluorescence: 2ug/ml
Western Blot: 1ug/ml
Immunocytochemistry: 2ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlRamos cell lysate
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, 0.02% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to human Casp-2 (NT) (ICH-1, Nedd2).
SpecificityRecognizes human Caspase-2 (NT). Species Crossreactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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