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You are here:Home » Antibodies » Abs to Apoptosis, Caspase » Anti -CASP2 (ICH-1, Nedd2, Caspase-2, CASP-2, Neural Precursor Cell Expressed Developmentally Down-regulated Protein 2, NEDD-2, Protease ICH-1)

Anti -CASP2 (ICH-1, Nedd2, Caspase-2, CASP-2, Neural Precursor Cell Expressed
Developmentally Down-regulated Protein 2, NEDD-2, Protease ICH-1)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Purified B IH
Caspases are a family of cysteine proteases that can be divided into the apoptotic and inflammatory caspase subfamilies. Unlike the apoptotic caspases, members of the inflammatory subfamily are generally not involved in cell death but are associated with the immune response to microbial pathogens. Members of this subfamily include caspase-1, -4, -5, and -12 and can activate proinflammatory cytokines such as IL-1b and IL-18. Although phylogenetically similar to this subfamily, Caspase-2 is thought to be involved in stress-induced apoptosis. Caspase-2 has two major isoforms; overexpression on the long form results in apoptosis while that of the short form suppresses cell death.
Catalog #C2086-72S
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:2000
Immunohistochemistry (Formalin fixed paraffin embedded): 1:200
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG2b,k
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in HEPES, 0.15M sodium chloride, 0.01% BSA, 0.03% sodium azide, 50% glycerol.
PurityPurified
ImmunogenSynthetic peptide corresponding to human CASP2.
SpecificityRecognizes human CASP2.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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