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You are here:Home » Antibodies » Abs to Apoptosis, Caspase » Anti -Caspase 8 (CASP8, CASP-8, ALPS2B, Apoptotic Cysteine Protease, Apoptotic Protease Mch-5, CAP4, FADD-homologous ICE/ced-3-like Protease, FADD-like ICE, FLICE, FLJ17672, ICE-like Apoptotic Protease 5, MORT1-associated Ced-3 Homolog, MACH, MCH5, MGC78473)

Anti -Caspase 8 (CASP8, CASP-8, ALPS2B, Apoptotic Cysteine Protease, Apoptotic Protease
Mch-5, CAP4, FADD-homologous ICE/ced-3-like Protease, FADD-like ICE, FLICE, FLJ17672,
ICE-like Apoptotic Protease 5, MORT1-associated Ced-3 Homolog, MACH, MCH5, MGC78473)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified E B IH
Caspase-8 is involved in the apoptosis mediated by CD95 and TNFR-1. It is suggested that following the triggering of apoptosis by CD95 or TNFR-1, the adaptor molecule FADD interact physically with cytosolic caspase-8 and initiate the apoptotic cascade. The active caspase-8 consists of two subunits of p18 and p10. This antibody should recognize the whole length of human caspase-8 and some isofrms of lower MW.
Catalog #C2087-42Y
ApplicationsSuitable for use in ELISA, Immunohistochemistry and Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-1ug/ml dilution buffer for each mini-gel
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2a
HostRat
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenFull length caspase-8 fusion protein
SpecificityRecognizes human Caspase-8.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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