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You are here:Home » Antibodies » Antibodies-Catenin » Anti -Catenin, beta

Anti -Catenin, beta


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Clone Host Grade Applications
Monoclonal Mouse Purified IH
b-Catenin (~92kD) shares 70% amino acid identity with both plakoglobin (g-catenin) and the product of the Drosophila segment polarity gene armadillo. b-catenin, plakoglobin (g-catenin), and p120 cas are homologous but distinct proteins which contain between 10-13 copies of a 42-44 amino acid motif rst identi ed in the armadillo protein and referred to as armadillo repeats. These armadillo repeats mediate b-cateninís interaction with the tumor suppressor protein APC (Adenomatous Polyposis Coli).
Catalog #C2096-59
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry: Frozen and formalin-fixed, paraffin embedded tissue sections. Epitope retrieval required.
Optimal dilutions to be determined by the researcher.
Recommended Positive Control TissueNon-neural epithelial tissue
Expected Staining Pattern Membrane and cytoplasmic
Epitope Retrieval: Required
Enzyme Digestion: Not required
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
Clone No3G67
FormSupplied as a liquid in PBS, pH 7.4, 1% BSA, 0.1% sodium azide.
PurityPuri ed from mouse ascites
ImmunogenRecombinant protein corresponding to the C-terminus of chicken b-catenin.
SpecificityRecognizes chicken b-catenin (~92kD) and does not crossreact with the related plakoglobin (~83kD) protein. Species Crossreactivity: human, mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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