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You are here:Home » Antibodies » Abs to Cathepsin » Anti -Cathepsin B (Cathepsin-B, CPSB, CTSB, Cathepsin B1, Amyloid Precursor Protein Secretase, APP Secretase, APPS, Preprocathepsin B, Procathepsin B)

Anti -Cathepsin B (Cathepsin-B, CPSB, CTSB, Cathepsin B1, Amyloid Precursor Protein
Secretase, APP Secretase, APPS, Preprocathepsin B, Procathepsin B)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Mouse Purified B
The protein encoded by this gene is a lysosomal cysteine proteinase composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. It is also known as amyloid precursor protein secretase and is involved in the proteolytic processing of amyloid precursor protein (APP). Incomplete proteolytic processing of APP has been suggested to be a causative factor in Alzheimer disease, the most common cause of dementia. Overexpression of the encoded protein, which is a member of the peptidase C1 family, has been associated with esophageal adenocarcinoma and other tumors. At least five transcript variants encoding the same protein have been found for this gene.
Catalog #C2097-03C
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.2.
PurityPurified.
ImmunogenCTSB (NP_001899.1, 1-339aa) full-length human protein.
SpecificityRecognizes human CTSB.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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