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Anti -Cathepsin D (CatD, CLN10, CPSD, CTSD, Lysosomal aspartyl peptidase, MGC2311 )
Anti -Cathepsin D (CatD, CLN10, CPSD, CTSD, Lysosomal aspartyl peptidase, MGC2311 )
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Ascites |
E B IH |
|
| Cathepsin D is an aspartyl protease expressed in all cells and has a role on the degradation of proteins in lysosomes. It is initially expressed as an inactive 52kD precursor and activated by proteolysis. | | | Catalog # | C2097-24F | | Applications | Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 1:1000. Band at 34kD and weaker band at 52kD | | Immunohistochemistry (Frozen sections and paraffin-embedded sections): 1:200 for paraffin sections | | Optimal dilutions to be determined by the researcher. | | Recommended Positive Controls | Human breast carcinoma or cell line extract. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG2a | | Clone No | 8J539 | | Host | Mouse | | Source | Human | | Concentration | Not Determined | | Form | Supplied as a liquid, 15mM sodium azide | | Purity | Ascites | | Immunogen | Full length purified native Cathepsin D from human liver. | | Cellular Localization | Lysosomal. | | Specificity | Recognizes human Cathepsin D. Does not react with bovine cathepsin D and B, or with human cathepsin types B, C, G or H. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | CatD, CLN10, CPSD, CTSD, Lysosomal aspartyl peptidase, MGC2311 |
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