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You are here:Home » Antibodies » Abs to Cathepsin » Anti -Cathepsin D (CTSD, CatD, CPSD)

Anti -Cathepsin D (CTSD, CatD, CPSD)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified E B IH
Cathepsin D is an aspartyl protease expressed in all cells and has a role on the degradation of proteins in lysosomes. It is initially expressed as an inactive 52kD precursor and activated by proteolysis. This antibody detects both precursor and mature forms. It does not react with human cathepsins B, C, G and H and with bovine cathepsins D and B.
Catalog #C2097-31C
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:500-1:2000
Immunohistochemistry (Formalin-fixed, paraffin-embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b,k
Clone No4G2
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
PurityPurified by Protein G affinity chromatography.
ImmunogenRecombinant corresponding to aa21-412 from human Cathepsin D, expressed in E. coli.
SpecificityRecognizes human CTSD.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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