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You are here:Home » Antibodies » Abs to Cathepsin » Anti -Cathepsin G (Cathepsin-G, CG, CTSG, CTSG Protein, MGC23078)

Anti -Cathepsin G (Cathepsin-G, CG, CTSG, CTSG Protein, MGC23078)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant B IH
Cathepsin G expression in normal tissues is restricted to granulocytes, especially neutrophils. However, mononuclear phagocytes have been demonstrated to bind and internalize proteases from neutrophils. Cathepsin G is located in neutrophilic polymorphonuclear leukocytes which contain specialized azurophil granules together with two other serine proteases; elastase and hepsin. These three proteases may participate in the killing and digestion of engulfed pathogens and in connective tissue remodelling at sites of inflammation. Cathepsin G is also reported to be expressed in acute and chronic myeloid leukemias whereas acute lymphoblastic or chronic lymphocytic leukemias are negative for this protein.
Catalog #C2097-49A
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:50
Immunohistochemistry: 1:100-1:200
Optimal dilutions to be determined by the researcher.
Positive ControlPBL cell line
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No9i239
HostMouse
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in 15mM sodium azide.
PuritySupernatant
ImmunogenProkaryotic recombinant protein corresponding to a 124aa, N-terminal region of human cathepsin G molecule.
SpecificityRecognizes human Cathepsin G.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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