Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications Monoclonal Mouse Affinity Purified E B

Cathepsin H is a lysosomal glycoprotein and a member of the cysteine proteinase. This cysteine protease class comprises cathepsin B, H, K, L, and O. These proteinases are viewed as simple mediators of lysosomal protein degradation. Cathepsin H is synthesized as an inactive proenzyme (41kDa) and then proteolytically processed to an active single chain, mature form (28kDa) within the endosomes/lysosomes. This proteinase is a peptidehydrolase that firstly isolated from rat liver, and then identified in liver, kidney, spleen, and brain of different mammals. Furthermore, cathepsin H is increased in disease states including breast carcinoma, melanoma, gliomas, and colorectal and prostate carcinoma.
Catalog #	C2097-61D
Applications	Suitable for use in ELISA and Western Blot. Other applications not tested.
Recommended Dilution	Western Blot: 1:500-1:2000
	Optimal dilutions to be determined by the researcher.
Hybridoma	Sp2/0 myeloma cells with spleen cells from Balb/c mice.
Storage and Stability	May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
CAS Number	n/a
Clone Type	Monoclonal
Isotype	IgG2a,k
Clone No	7G23
Host	Mouse
Source	Human
Concentration	~1mg/ml
Form	Supplied as a liquid in PBS, pH 7.4, 0.02% thimerosal
Purity	Purified by Protein G affinity chromatography.
Immunogen	Recombinant human cathepsin H (23-335 aa) (E. coli)
Specificity	Recognizes human Cathepsin H
Important Note	This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.