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You are here:Home » Antibodies » Abs to Cathepsin » Anti -CTSK (Cathepsin K, Cathepsin O, Cathepsin X, Cathepsin O2, CTSO2, CTSO)

Anti -CTSK (Cathepsin K, Cathepsin O, Cathepsin X, Cathepsin O2, CTSO2, CTSO)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP IH
The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. This gene may be subject to RNA editing.
Catalog #C2097-69N
ApplicationsSuitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-4ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
HostRabbit
SourceRat
Concentration~0.1mg/ml
FormSupplied as a liquid in PBS, pH7.2, 30% glycerol, 0.5% BSA, 0.01% thimerosal.
PurityPurified by Protein A affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa321 of rat cathepsin K.
SpecificityRecognizes rat CTSK. Species Crossreactivity: mouse, human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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