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You are here:Home » Antibodies » Abs to Cathepsin » Anti -CTSL1, ID (Cathepsin L1, Major Excreted Protein, MEP, Cathepsin L1 Heavy Chain, Cathepsin L1 Light Chain, CTSL)

Anti -CTSL1, ID (Cathepsin L1, Major Excreted Protein, MEP, Cathepsin L1 Heavy Chain,
Cathepsin L1 Light Chain, CTSL)

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Purified E B IH
Cathepsins are lysosomal proteases that play an important role in the intracellular degradation of exogenous and endogenous proteins, activation of enzyme precursors, and tumor invasion and metastasis. Normally located in lysosomes of almost all mammalian cells, they can be secreted from the cell under certain conditions. Cathepsin L is responsible for most of the intralysosomal breakdown of normal cells. Cathepsin L is secreted by numerous transformed cells in its inactive proform, and mRNA expression level seems to correlate with their metastatic potential.
Catalog #C2097-70P
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-1:2000
Immunohistochemistry (Formalin-fixed, paraffin-embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG2b,k
Clone No2H7
HostMouse
SourceHuman
ConcentrationAs reported
FormSupplied as a liquid in PBS, pH 7.4, 0.1% sodium azide.
PurityPurified
ImmunogenRecombinant corresponding to aa114-333 from human Cathepsin L, expressed in E. coli.
SpecificityRecognizes human CTSL1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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