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You are here:Home » Antibodies » Abs to Ion Channel » Anti -Cav1.2 alpha1c (Voltage-dependent L-type calcium channel subunit alpha-1C, Voltage-gated calcium channel subunit alpha Cav1.2, Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle, Mouse brain class C, MBC, MELC-CC, Cacna1c, Cach2, Cacn

Anti -Cav1.2 alpha1c (Voltage-dependent L-type calcium channel subunit alpha-1C,
Voltage-gated calcium channel subunit alpha Cav1.2, Calcium channel, L type, alpha-1
polypeptide, isoform 1, cardiac muscle, Mouse brain class C, MBC, MELC-CC, Cacna1c, Cach2,
Cacn

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Many alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized.
Catalog #C2097-85G
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000 detects Cav1.2 alpha1c on mouse pancreas lysate
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.  
Clone TypePolyclonal
IsotypeIgG
HostRabbit
Concentration~1mg/ml
FormSupplied as a liquid in 0.1M Tris-Glycine, pH7.4, 150mM sodium chloride, 0.05% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the N-terminus region of human Cav1.2 alpha1c, conjugated to KLH.
SpecificityRecognizes Cav1.2 alpha1c at ~170-240kD.
Species crossreactivityMouse. Species sequence homology: human (100%); rat, opposum (93.3%).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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