Anti -Cav1.2 alpha1c (Voltage-dependent L-type calcium channel subunit alpha-1C,
Voltage-gated calcium channel subunit alpha Cav1.2, Calcium channel, L type, alpha-1
polypeptide, isoform 1, cardiac muscle, Mouse brain class C, MBC, MELC-CC, Cacna1c, Cach2,
Cacn
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B |
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| This gene encodes an alpha-1 subunit of a voltage-dependent calcium channel. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization. The alpha-1 subunit consists of 24 transmembrane segments and forms the pore through which ions pass into the cell. The calcium channel consists of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. There are multiple isoforms of each of these proteins, either encoded by different genes or the result of alternative splicing of transcripts. The protein encoded by this gene binds to and is inhibited by dihydropyridine. Many alternate transcriptional splice variants of this gene have been observed but have not been thoroughly characterized. | | | Catalog # | C2097-85G | | Applications | Suitable for use in Western Blot. Other applications not tested. | | Recommended Dilution | Western Blot: 1:1000 detects Cav1.2 alpha1c on mouse pancreas lysate | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in 0.1M Tris-Glycine, pH7.4, 150mM sodium chloride, 0.05% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to the N-terminus region of human Cav1.2 alpha1c, conjugated to KLH. | | Specificity | Recognizes Cav1.2 alpha1c at ~170-240kD. | | Species crossreactivity | Mouse. Species sequence homology: human (100%); rat, opposum (93.3%). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -Cav1.2 alpha1c (Voltage-dependent L-type calcium channel subunit alpha-1C, Voltage-gated calcium channel subunit alpha Cav1.2, Calcium channel, L type, alpha-1 polypeptide, isoform 1, cardiac muscle, Mouse brain class C, MBC, MELC-CC, Cacna1c, Cach2, Cacn |
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