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You are here:Home » Antibodies » Abs to Membrane Proteins » Anti -Caveolin 1 (CAV1, Caveolae protein, HGNC:1527, CAV, MSTP085, Cell Growth-inhibiting Protein 32, VIP21)

Anti -Caveolin 1 (CAV1, Caveolae protein, HGNC:1527, CAV, MSTP085, Cell Growth-inhibiting
Protein 32, VIP21)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified B IP IF
Caveolae are specialized domains of the plasma membrane that are implicated in the sequestration of a variety of lipid and protein molecules. It has been suggested that these important cellular organelles have a pivotal role in such diverse biochemical processes as lipid metabolism, growth regulation, signal transduction, and apoptosis. Caveolin interacts with and regulates heterotrimeric G-proteins. Currently, there are three members of the caveolin multigene family which are known to encode 21-24kD integral membrane proteins that comprise the major structural component of the caveolar membrane in vivo. Caveolin-2 protein is abundantly expressed in fibroblasts and differentiated adipocytes, smooth and skeletal muscle, and endothelial cells. The expression of caveolin-1 is similar to that of caveolin-2 while caveolin-3 expression appears to be limited to muscle tissue types.
Catalog #C2097-91Q
ApplicationsSuitable for use in Immunofluorescence, Western Blot and Immunoprecipitation. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000-1:4000
Immunofluorescence: 1:200
Optimal dilutions to be determined by the researcher.
Positive ControlA431 and 3T3 whole cell lysates
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2b
Clone No8J542
HostMouse
Concentration~2mg/ml
FormSupplied as a liquid in tris-glycine, 150mM NaCl, 0.05% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenGlut 4 vesicles.
SpecificityRecognizes caveolin alpha and beta proteins. Species Crossreactivity: rat, human and mouse. Other species have not been tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCAV1, Caveolae protein, HGNC:1527, CAV, MSTP085, Cell Growth-inhibiting Protein 32, VIP21


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