Anti -Caveolin 1 (CAV1, Caveolae protein, HGNC:1527, CAV, MSTP085, Cell Growth-inhibiting
Protein 32, VIP21)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP IC IF |
|
| Caveolae are specialized domains of the plasma membrane that are implicated in the sequestration of a variety of lipid and protein molecules. It has been suggested that these important cellular organelles have a pivotal role in such diverse biochemical processes as lipid metabolism, growth regulation, signal transduction, and apoptosis. Caveolin interacts with and regulates heterotrimeric G-proteins. Currently, there are three members of the caveolin multigene family which are known to encode 21-24kD integral membrane proteins that comprise the major structural component of the caveolar membrane in vivo. Caveolin-2 protein is abundantly expressed in fibroblasts and differentiated adipocytes, smooth and skeletal muscle, and endothelial cells. The expression of caveolin-1 is similar to that of caveolin-2 while caveolin-3 expression appears to be limited to muscle tissue types. | | | Catalog # | C2097-91R | | Applications | Suitable for use in Western Blot, Immunoprecipitation, Immunocytochemistry, and Immunofluorescence. Other applications not tested. | | Recommended Dilution | Western Blot” 1-2ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in PBS with 1 mg/ml BSA and 0.05% sodium azide | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide (MSGGKYVDSEGHLYTVP-C) corresponding to amino acid residues 1-17 of human caveolin-1 (added with C-terminal cysteine for conjugation). This sequence is completely conserved between human, mouse, canine, bovine, and rat. | | Specificity | Detects caveolin-1. Species Crossreactivity: Crossreacts with human, rat, mouse, canine and hamster. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | CAV1, Caveolae protein, HGNC:1527, CAV, MSTP085, Cell Growth-inhibiting Protein 32, VIP21 |
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