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You are here:Home » Antibodies » Abs to Membrane Proteins » Anti -Caveolin 1 (Caveolin-1, CAV 1, CAV1, CAV-1, CAV, Caveolae Protein 22 kD, Cell Growth-inhibiting Protein 32, HGNC:1527, MSTP085, OTTHUMP00000025031, VIP21)

Anti -Caveolin 1 (Caveolin-1, CAV 1, CAV1, CAV-1, CAV, Caveolae Protein 22 kD, Cell
Growth-inhibiting Protein 32, HGNC:1527, MSTP085, OTTHUMP00000025031, VIP21)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B
Cav1 is a 21kD scaffolding protein which is the main component of the caveolae plasma membranes found in most cell types. Two isoforms (alpha and beta) are encoded by a single transcript from this gene. Cav1 is highly expressed in terminally differentiated or quiescent cells, suggesting a possible role for Cav1 as a negative regulator of cell proliferation. Cav1 has been implicated in the pathogenesis of oncogenic cell transformation, tumorigenesis, and metastasis
and functions as a “tumor and/or metastasis-modifying gene”. For example Cav1 normally functions as a negative regulator of cell transformation and mammary tumorigenesis, whilst in prostate cancers Cav1 may function as a tumor promoter.
Catalog #C2097-91T
ApplicationsSuitable for use in ELISA and Western Blot. Other applications not tested.
Recommended DilutionELISA: 1:32,000
Western Blot: 0.3-1.0ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in Tris-saline, pH7.3, 0.02% sodium azide, 0.5% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide, C-DELSEKQVYDAH, corresponding to from internal region of Caveolin 1.
SpecificityRecognizes human CAVEOLIN 1. Species sequence homology: rat, mouse, canine and porcine.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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