Anti -Caveolin 1, CT (Caveolin-1, CAV 1, CAV1, CAV-1, CAV, Caveolae Protein 22 kD, Cell
Growth-inhibiting Protein 32, HGNC:1527, MSTP085, OTTHUMP00000025031, VIP21)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP IF |
|
| Caveolae are specialized domains of the plasma membrane that are implicated in the sequestration of a variety of lipid and protein molecules. It has been suggested that these important cellular organelles have a pivotal role in such diverse biochemical processes as lipid metabolism, growth regulation, signal transduction, and apoptosis. Caveolin interacts with and regulates heterotrimeric G-proteins. Currently, there are three members of the caveolin multigene family which are known to encode 21-24 kDa integral membrane proteins that comprise the major structural component of the caveolar membrane in vivo. Caveolin-2 protein is abundantly expressed in fibroblasts and differentiated adipocytes, smooth and skeletal muscle, and endothelial cells. The expression of caveolin-1 is similar to that of caveolin-2 while caveolin-3 expression appears to be limited to muscle tissue types. | | | Catalog # | C2097-93D | | Applications | Suitable for use in Western Blot, Immunofluorescence and Immunoprecipitation. Other applications not tested. | | Recommended Dilution | immunofluorescence 1:200 | | immunoprecipitation 5-10ug/ml, | | Western Blot 1:5000, where a band is seen ~22 kD. | | Optimal dilution determined by the researcher. | | Positive Controls | HeLa whole cell extract | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile glycerol (40-50%), aliquot and store at -20°C. Aliquots are stable for at least 3 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Rabbit | | Source | Rat | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, 0.04% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide made to an N-terminal portion of the rat protein (within residues 1-150). Cellular Localization: membrane. | | Specificity | Recognizes rat Caveolin 1. Species Crossreactivity: human, mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | Caveolin 1 alpha Isoform, Caveolin 1 beta Isoform |
|
|
Questions or comments about this product? Inquire here. |
|
|
Download Specifications for Anti -Caveolin 1, CT (Caveolin-1, CAV 1, CAV1, CAV-1, CAV, Caveolae Protein 22 kD, Cell Growth-inhibiting Protein 32, HGNC:1527, MSTP085, OTTHUMP00000025031, VIP21) |
External Links
|
