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You are here:Home » Antibodies » Abs to Membrane Proteins » Anti -Caveolin 1, NT (Caveolin-1, CAV 1, CAV1, CAV-1, CAV, Caveolae Protein 22 kD, Cell Growth-inhibiting Protein 32, HGNC:1527, MSTP085, OTTHUMP00000025031, VIP21)

Anti -Caveolin 1, NT (Caveolin-1, CAV 1, CAV1, CAV-1, CAV, Caveolae Protein 22 kD, Cell
Growth-inhibiting Protein 32, HGNC:1527, MSTP085, OTTHUMP00000025031, VIP21)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP IF
Caveolae are specialized domains of the plasma membrane that are implicated in the sequestration of a variety of lipid and protein molecules. It has been suggested that these important cellular organelles have a pivotal role in such diverse biochemical processes as lipid metabolism, growth regulation, signal transduction, and apoptosis. Caveolin interacts with and regulates heterotrimeric G-proteins. Currently, there are three members of the caveolin multigene family which are known to encode 21-24kD integral membrane proteins that comprise the major structural component of the caveolar membrane in vivo. Caveolin-2 protein is abundantly expressed in fibroblasts and differentiated adipocytes, smooth and skeletal muscle, and endothelial cells. The expression of caveolin-1 is similar to that of caveolin-2 while caveolin-3 expression appears to be limited to muscle tissue types.
Catalog #C2097-93D
ApplicationsSuitable for use in Western Blot, Immunofluorescence and Immunoprecipitation. Other applications not tested.
Recommended DilutionsImmunofluorescence (IC): 1:200
Immunoprecipitation: 5-10ug/ml
Western Blot: 1:5000 detects a band at~22kD.
Optimal dilution determined by the researcher.
Positive ControlHeLa whole cell extract
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceRat
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.04% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa1-150 at the N-terminal of rat Caveolin 1. Cellular Localization: Membrane
SpecificityRecognizes rat Caveolin 1. Species Crossreactivity: human and mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCaveolin 1 alpha Isoform, Caveolin 1 beta Isoform


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