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You are here:Home » Antibodies » Abs to Membrane Proteins » Anti -Caveolin 3 (CAV 3, CAV3, Caveolin3, LGMD1C, M caveolin, MGC126100, MGC126101, MGC126129, VIP 21, VIP21)

Anti -Caveolin 3 (CAV 3, CAV3, Caveolin3, LGMD1C, M caveolin, MGC126100, MGC126101,
MGC126129, VIP 21, VIP21)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IP IH
This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites.
Catalog #C2097-98A
ApplicationsSuitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin-embedded sections): 1:500
Western Blot: 1ug/ml. Detects caveolin 3 from rat heart homogenate at ~21kD.
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 1mg/ml BSA., 0.05% sodium azide
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to aa1-18, M(1)MTEEHTDLEARIIKDIH(18) C, of human caveolin-3. This sequence is completely conserved in mouse caveolin-3.
SpecificityRecognizes human caveolin-3. Does not react with caveolin-1 or -2. Species Crossreactivity: rat and mouse
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCAV 3, CAV3, Caveolin3, LGMD1C, M caveolin, MGC126100, MGC126101, MGC126129, VIP 21, VIP21


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