Anti -Caveolin 3 (CAV 3, CAV3, Caveolin3, LGMD1C, M caveolin, MGC126100, MGC126101,
MGC126129, VIP 21, VIP21)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IP IH |
|
| This gene encodes a caveolin family member, which functions as a component of the caveolae plasma membranes found in most cell types. Caveolin proteins are proposed to be scaffolding proteins for organizing and concentrating certain caveolin-interacting molecules. Mutations identified in this gene lead to interference with protein oligomerization or intra-cellular routing, disrupting caveolae formation and resulting in Limb-Girdle muscular dystrophy type-1C (LGMD-1C), hyperCKemia or rippling muscle disease (RMD). Alternative splicing has been identified for this locus, with inclusion or exclusion of a differentially spliced intron. In addition, transcripts utilize multiple polyA sites and contain two potential translation initiation sites. | | | Catalog # | C2097-98A | | Applications | Suitable for use in Western Blot, Immunoprecipitation and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (paraffin-embedded sections): 1:500 | | Western Blot: 1ug/ml. Detects caveolin 3 from rat heart homogenate at ~21kD. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, 1mg/ml BSA., 0.05% sodium azide | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to aa1-18, M(1)MTEEHTDLEARIIKDIH(18) C, of human caveolin-3. This sequence is completely conserved in mouse caveolin-3. | | Specificity | Recognizes human caveolin-3. Does not react with caveolin-1 or -2. Species Crossreactivity: rat and mouse | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. | | Alternate names | CAV 3, CAV3, Caveolin3, LGMD1C, M caveolin, MGC126100, MGC126101, MGC126129, VIP 21, VIP21 |
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