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You are here:Home » Antibodies » Abs to Chromatin Proteins » Anti -CBX3 (Chromobox Homolog 3, HECH, Heterochromatin Protein 1 Homolog gamma, HP1-gamma, HP1Hs-g)

Anti -CBX3 (Chromobox Homolog 3, HECH, Heterochromatin Protein 1 Homolog gamma, HP1-gamma,
HP1Hs-g)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IP
CBX3 seems to be involved in transcriptional silencing in heterochromatin-like complexes. It recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. It may contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). In addition, it is involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.
Catalog #C2098-70C
ApplicationsSuitable for use in Immunoprecipitation. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormTris-citrate/phosphate buffer, pH 7 to 8
PurityPurified by immunoaffinity chromatography.
ImmunogenA synthetic peptide mapping to a region between residue 133 and the C-terminus (residue 183) of human chromobox homolog 3 using the numbering given in entry NP_009207.2 (GeneID 11335).
SpecificitySpecies Crossreactivity: Human. Other species not tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCBX3, chromobox homolog 3, HECH, HP1-Gamma, HP1Hs-Gamma, Heterochromatin Protein HP1 Gamma


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