You are here:Home
»
Antibodies
»
Abs to Chromatin Proteins
»
Anti -CBX3, ID (Chromobox Protein Homolog 3, HECH, Heterochromatin Protein 1 Homolog gamma, HP1 gamma, Modifier 2 Protein)
Anti -CBX3, ID (Chromobox Protein Homolog 3, HECH, Heterochromatin Protein 1 Homolog
gamma, HP1 gamma, Modifier 2 Protein)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B IH |
|
| CBX3 seems to be involved in transcriptional silencing in heterochromatin-like complexes. It recognizes and binds histone H3 tails methylated at 'Lys-9', leading to epigenetic repression. It may contribute to the association of the heterochromatin with the inner nuclear membrane through its interaction with lamin B receptor (LBR). In addition, it is involved in the formation of functional kinetochore through interaction with MIS12 complex proteins. | | | Catalog # | C2098-70J | | Applications | Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | ELISA: 1:32,000 | | Western Blot: 0.3-1ug/ml | | Immunohistochemistry (Formalin fixed paraffin embedded): 2.5ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Host | Goat | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in TBS, 0.5% BSA, 0.02% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to Internal Region of CBX3/HP1 Gamma: EAFLNSQKAGKEKD (KLH). | | Specificity | Recognizes human CBX3. Species sequence homology: Canine, mouse and rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
