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You are here:Home » Antibodies » Abs to Chromatin Proteins » Anti -CBX4 (chromobox homolog 4 (Drosophila Pc class), Chromobox protein homolog 4, E3 SUMO-protein Ligase CBX4, MGC143697, MGC143698, mPc2, MPc2, Pc2, PC2, Polycomb 2 Homolog)

Anti -CBX4 (chromobox homolog 4 (Drosophila Pc class), Chromobox protein homolog 4, E3
SUMO-protein Ligase CBX4, MGC143697, MGC143698, mPc2, MPc2, Pc2, PC2, Polycomb 2 Homolog)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
The family of Heterochromatin Proteins ("Chromobox Homolog", CBX) are highly conserved adapter molecules, which have important functions in the cell nucleus. These functions include gene repression by heterochromatin formation, transcriptional activation, regulation of binding of cohesion complexes to centromere, sequesteration of genes to nuclear periphery, transcriptional arrest, maintenance of heterochromatin integrity, gene repression at single nucleosome level, and gene repression by heterochromatization of euchromatin.
Catalog #C2098-79A
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-2ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlNIH/3T3 nuclear extract, HeLa cell nuclear extract
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceMouse
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.05% sodium azide.
PurityPurified by Protein A affinity chromatography.
ImmunogenGST-tagged recombinant protein corresponding to the postchromo domain of CBX4. Cellular Localization: Nucleus
SpecificityRecognizes the postchromo domain of mouse CBX4. Species Crossreactivity: human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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