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You are here:Home » Antibodies » Abs to Chromatin Proteins » Anti -CBX8 (CBX-8, Chromobox Homolog 8, PC3, HPC3, Human Polycomb 3, RC1)

Anti -CBX8 (CBX-8, Chromobox Homolog 8, PC3, HPC3, Human Polycomb 3, RC1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IP
Component of the Polycomb group (PcG) multiprotein PRC1 complex, a complex required to maintain the transcriptionally repressive state of many genes, including Hox genes, throughout development. PcG PRC1 complex acts via chromatin remodeling and modification of histones; it mediates monoubiquitination of histone H2A 'Lys-119', rendering chromatin heritably changed in its expressibility (By similarity).
Catalog #C2098-89A
ApplicationsSuitable for use in ELISA, Western Blotting, Immunoprecipitation. Other applications not tested.
Recommended DilutionWestern Blotting: 1:1000-1:2000
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid Tris-citrate/phosphate buffer, pH 7 to 8.
PurityPurified by peptide immunoaffinity chromatography.
ImmunogenThe epitope recognized maps to a region between residue 350 and the C-terminus (residue 389) of human Chromobox homolog 8 using the numbering given in entry NP_065700.1 (GeneID 57332).
SpecificityThis antibody is specific to the CBX8 protein. Species Crossreactivity: Human. Other species not yet tested.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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