Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to G Proteins » Anti -CCR1 (Chemokine Receptor 1, CC-CCR-1, CD191, Macrophage inflammatory protein 1-alpha receptor, RANTES-R, HM145, LD78 receptor, CMKBR1, CMKR1, SCYAR1)

Anti -CCR1 (Chemokine Receptor 1, CC-CCR-1, CD191, Macrophage inflammatory protein 1-alpha
receptor, RANTES-R, HM145, LD78 receptor, CMKBR1, CMKR1, SCYAR1)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH FC
CCR1 (C-C chemokine receptor type 1) is a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, expressed by a wide range of cells, which acts as a vital signal transducer for the recruitment of effector immune cells to inflammation sites, and may play a role in the regulation of Th1/Th2 cytokine responses. CCR1 binds to several immunoregulatory chemokines, including MIP-1 alpha (macrophage inflammatory protein 1 alpha), MIP-1 delta, MCP-3 (monocyte chemoattractant protein 3) and RANTES (regulated on activation normal T expressed and secreted protein). Studies have also shown that CCR1 binds with high affinity to viral MIP-2, displacing its normal ligands.
Catalog #C2099-65J
ApplicationsSuitable for use in Flow Cytometry, ELISA, Western Blot and Immunohistology. Other applications not tested.
Recommended DilutionFlow Cytometry: 1:200; 10ul labels 10e6 cells in 100ul
ELISA: 1:50,000
Western Blot: 1:1000.
Immunohistology: 1:300
Optimal dilutions to be determined by the researcher.
Positive ControlTonsil or spleen
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in pH7.2, 0.09% sodium azide, 0.1% bovine serum.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide TEDYDTTTEFDYGDATPC corresponding to aa7-24 of human CCR1.
SpecificityRecognizes human CCR1.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links