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You are here:Home » Antibodies » Abs to G Proteins » Anti -CCR1 (C-C Chemokine Receptor Type 1, C-C CKR-1, CC-CKR-1, CCR-1, CCR1, HM145, LD78 Receptor, Macrophage Inflammatory Protein 1-alpha Receptor, MIP-1alpha-R, RANTES-R, CD191, CMKBR1, CMKR1, SCYAR1)

Anti -CCR1 (C-C Chemokine Receptor Type 1, C-C CKR-1, CC-CKR-1, CCR-1, CCR1, HM145, LD78
Receptor, Macrophage Inflammatory Protein 1-alpha Receptor, MIP-1alpha-R, RANTES-R, CD191,
CMKBR1, CMKR1, SCYAR1)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
CCR1 (C-C chemokine receptor type 1) is a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, expressed by a wide range of cells, which acts as a vital signal transducer for the recruitment of effector immune cells to inflammation sites, and may play a role in the regulation of Th1/Th2 cytokine responses. CCR1 binds to several immunoregulatory chemokines, including MIP-1 alpha (macrophage inflammatory protein 1 alpha), MIP-1 delta, MCP-3 (monocyte chemoattractant protein 3) and RANTES (regulated on activation normal T expressed and secreted protein). Studies have also shown that CCR1 binds with high affinity to viral MIP-2, displacing its normal ligands.
Catalog #C2099-65K
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1-3ug/ml
Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.05% sodium azide, 0.2% gelatin.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to human CCR1 (KLH).
SpecificityRecognizes human CCR1. Species sequence homology: Mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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