Anti -CCR1 (C-C Chemokine Receptor Type 1, C-C CKR-1, CC-CKR-1, CCR-1, CCR1, HM145, LD78 Receptor, Macrophage Inflammatory Protein 1-alpha Receptor, MIP-1alpha-R, RANTES-R, CD191, CMKBR1, CMKR1, SCYAR1)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
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| CCR1 (C-C chemokine receptor type 1) is a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, expressed by a wide range of cells, which acts as a vital signal transducer for the recruitment of effector immune cells to inflammation sites, and may play a role in the regulation of Th1/Th2 cytokine responses. CCR1 binds to several immunoregulatory chemokines, including MIP-1 alpha (macrophage inflammatory protein 1 alpha), MIP-1 delta, MCP-3 (monocyte chemoattractant protein 3) and RANTES (regulated on activation normal T expressed and secreted protein). Studies have also shown that CCR1 binds with high affinity to viral MIP-2, displacing its normal ligands. | | | Catalog # | C2099-65K | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 1-3ug/ml | | Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a liquid in PBS, 0.05% sodium azide, 0.2% gelatin. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Synthetic peptide corresponding to human CCR1 (KLH). | | Specificity | Recognizes human CCR1. Species sequence homology: Mouse. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -CCR1 (C-C Chemokine Receptor Type 1, C-C CKR-1, CC-CKR-1, CCR-1, CCR1, HM145, LD78 Receptor, Macrophage Inflammatory Protein 1-alpha Receptor, MIP-1alpha-R, RANTES-R, CD191, CMKBR1, CMKR1, SCYAR1) |
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