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You are here:Home » Antibodies » Abs to G Proteins » Anti -CCR1 (C-C Chemokine Receptor Type 1, C-C CKR-1, CC-CKR-1, CCR-1, CCR1, HM145, LD78 Receptor, Macrophage Inflammatory Protein 1-alpha Receptor, MIP-1alpha-R, RANTES-R, CD191, CMKBR1, CMKR1, SCYAR1)

Anti -CCR1 (C-C Chemokine Receptor Type 1, C-C CKR-1, CC-CKR-1, CCR-1, CCR1, HM145, LD78
Receptor, Macrophage Inflammatory Protein 1-alpha Receptor, MIP-1alpha-R, RANTES-R, CD191,
CMKBR1, CMKR1, SCYAR1)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Chemokines play an important role in inflammation and are critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors. The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR1, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds the leukocyte chemoattractant and hemopoiesis regulator macrophage-inflammatory protein (MIP-1), eotaxin, as well as several other related chemokines. Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation.
Catalog #C2099-65L
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 0.5-4ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, 0.5% BSA, 0.01% thimerosal, 30% glycerol.
PurityPurified by affinity chromatography.
ImmunogenSynthetic peptide corresponding to aa341 from human CCR1.
SpecificityRecognizes human CCR1 at ~42kD. Species Crossreactivity: mouse and monkey.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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