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Anti -CCR2 (NT) (CD192, C-C chemokine receptor type 2, C-C CKR-2, Monocyte chemoattractant protein 1 receptor, MCP-1-R, CMKBR2)
Anti -CCR2 (NT) (CD192, C-C chemokine receptor type 2, C-C CKR-2, Monocyte chemoattractant
protein 1 receptor, MCP-1-R, CMKBR2)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Goat |
Affinity Purified |
E B IH |
|
| CCR2 (C-C chemokine receptor type 2 is, a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, which acts as a receptor for the chemokines MCP-1 (monocyte chemoattractant protein 1), MCP-3 and MCP-4. Interaction between CD192 and MCP-1 initiates chemotactic responses, through an increase in intracellular calcium levels. CD192 acts as a co-receptor with CD4 for HIV1 infection, and variations in CD192 are associated with relative resistance to HIV1. | | | Catalog # | C2099-66J | | Applications | Suitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | ELISA: 1:60,000 | | Western Blotting: 1:1000 | | Immunohistochemistry (paraffin): 1:200 | | Optimal dilutions to be determined by the researcher. | | Positive Control | Spleen | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Goat | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in 10mM KHPO4, 140mM sodium chloride, pH7.2, 0.09% sodium azide, 0.1% BSA. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide CGEEVTTFFDYDYGAPCHKFDVKQ corresponding to aa17-39 within the N-terminal region of human CCR2. | | Specificity | Recognizes an epitope within the N-terminal region of human CCR2. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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