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You are here:Home » Antibodies » Antibodies-G Proteins » Anti -CCR5 (Chemokine Receptor 5, CC-CKR-5, CD195, C-C chemokine receptor type 5, HIV-1 fusion coreceptor, CHEMR13, CMKBR5)

Anti -CCR5 (Chemokine Receptor 5, CC-CKR-5, CD195, C-C chemokine receptor type 5, HIV-1
fusion coreceptor, CHEMR13, CMKBR5)


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Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
CCR5 (C-C chemokine receptor type 5) is a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, preferentially expressed by a subset of memory Th1 (type 1 helper T) cells. CCR5 acts as a high-affinity receptor for several chemotactic chemokines, including MIP-1 alpha (macrophage inflammatory protein 1 alpha), MIP-1 beta, and RANTES (regulated on activation normal T expressed and secreted protein). CCR5 is also a major co-receptor for HIV-1 infection, with variations in the CCR5 gene, influencing the rate of progression into AIDS.
Catalog #C2099-69G
ApplicationsSuitable for use in ELISA, Western Blot, and Immunohistochemistry (frozen, paraffin). Other applications not tested.
Recommended DilutionELISA: 1:50000
Western Blot: 1:1000
Immunohistochemistry (paraffin): 1:300 (May require antigen retrieval using EDTA buffer)
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
FormSupplied as a liquid in 10mM KHPO4, 140mM sodium chloride, pH7.2, 0.09% sodium azide, 0.1% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide YQVSSPIYDINYYTSEPCQKINVKQIAA corresponding to aa3-30 within the N-terminal region of human CCR5.
SpecificityRecognizes an epitope within the N-terminal region of human CCR5. Species Crossreactivity: macaque.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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