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You are here:Home » Antibodies » Abs to G Proteins » Anti -CCR5 (Chemokine Receptor 5, CC-CKR-5, CD195, C-C chemokine receptor type 5, HIV-1 fusion coreceptor, CHEMR13, CMKBR5)

Anti -CCR5 (Chemokine Receptor 5, CC-CKR-5, CD195, C-C chemokine receptor type 5, HIV-1
fusion coreceptor, CHEMR13, CMKBR5)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
CCR5 (C-C chemokine receptor type 5) is a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, preferentially expressed by a subset of memory Th1 (type 1 helper T) cells. CCR5 acts as a high-affinity receptor for several chemotactic chemokines, including MIP-1 alpha (macrophage inflammatory protein 1 alpha), MIP-1 beta, and RANTES (regulated on activation normal T expressed and secreted protein). CCR5 is also a major co-receptor for HIV-1 infection, with variations in the CCR5 gene, influencing the rate of progression into AIDS.
Catalog #C2099-69G
ApplicationsSuitable for use in ELISA, Western Blot, and Immunohistochemistry (frozen, paraffin). Other applications not tested.
Recommended DilutionELISA: 1:50000
Western Blot: 1:1000
Immunohistochemistry (paraffin): 1:300 (May require antigen retrieval using EDTA buffer)
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in 10mM KHPO4, 140mM sodium chloride, pH7.2, 0.09% sodium azide, 0.1% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide YQVSSPIYDINYYTSEPCQKINVKQIAA corresponding to aa3-30 within the N-terminal region of human CCR5.
SpecificityRecognizes an epitope within the N-terminal region of human CCR5. Species Crossreactivity: macaque.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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