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You are here:Home » Antibodies » Abs to G Protein Receptors » Anti -CCR6 (CD196, Chemokine Receptor 6, CC-CCR-6, C-C chemokine receptor type 6, LARC receptor, GPR-CY4, Chemokine receptor-like 3, DRY6, G-protein coupled receptor 29, CKRL3, CMKBR6, GPR29, STRL22)

Anti -CCR6 (CD196, Chemokine Receptor 6, CC-CCR-6, C-C chemokine receptor type 6, LARC
receptor, GPR-CY4, Chemokine receptor-like 3, DRY6, G-protein coupled receptor 29, CKRL3,
CMKBR6, GPR29, STRL22)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
CCR6 (C-C chemokine receptor type 6) is a transmembrane glycoprotein and member of the G-protein coupled receptor 1 family, which acts as a specific receptor for the C-C chemokine LARC (Liver and activation-regulated chemokine)/MIP-3alpha, a selective chemoattractant which induces calcium flux in CCR6-expressing lymphocytes. CCR6 is preferentially expressed by B cells, memory T cells and immature dendritic cells and plays an important role in B lineage maturation and antigen-driven B cell differentiation. CCR6 acts as a co-receptor for HIV1 infection, and is selectively expressed by mucosa-associated non-Hodgkin's lymphoma, making the interaction between CCR6 and LARC a potential therapeutic target in these malignancies.
Catalog #C2099-70D
ApplicationsSuitable for use in ELISA, Western Blot, and Immunohistochemistry. Other applications not tested.
Recommended DilutionELISA: 1:75,000
Western Blot: 1:500
Immunohistochemistry (resin): 1:250
Optimal dilutions to be determined by the researcher.
Positive ControlSpleen
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in 10mM KHPO4, 140mM sodium chloride, pH7.2, 0.09% sodium azide, 0.1% BSA.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide YFVSVNTSYYSVDSEMLLCSLQEVRQFSR corresponding to aa8-46 of human CCR6.
SpecificityRecognizes human CCR6. Species Cross Reactivity: mouse.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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