Anti -CCR6 (Chemokine (C-C motif) Receptor 6, C-C Chemokine Receptor Type 6, C-C CKR-6, CCR-6, CKR6, BN-1, CD196, Chemokine Receptor-like 3, CKRL3, CKR-L3, CMKBR6, DCR2, DRY6, DRY-6, GPRCY4, GPR-CY4, G-protein Coupled Receptor 29, GPR29, LARC Receptor, STRL22)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
E B |
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| CCR6, otherwise known as CD196, is a multi-pass type 3 glycoprotein and member of the G-protein coupled receptor 1 family, which acts as a specific receptor for the C-C chemokine LARC (Liver and activation-regulated chemokine)/MIP-3alpha, a selective chemoattractant which induces calcium flux in CD196-expressing lymphocytes. CD196 is preferentially expressed by B cells, memory T cells and immature dendritic cells and properties attributed to CD196 include involvement in B lineage maturation and B cell differentiation, possible regulation of immune cell trafficking during inflammatory responses, and a co-receptor for HIV-1 infection. | | | Catalog # | C2099-70E | | Applications | Suitable for use in ELISA and Western Blot. Other applications not tested. | | Recommended Dilution | | | Western Blot: 1:500-1:1,000 | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, add sterile 40-50% glycerol, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 10B946 | | Host | Mouse | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.09% sodium azide. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Recombinant human CD196 (aa1-46) purified from E. coli. | | Specificity | Recognizes human CCR6 at ~50kD. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -CCR6 (Chemokine (C-C motif) Receptor 6, C-C Chemokine Receptor Type 6, C-C CKR-6, CCR-6, CKR6, BN-1, CD196, Chemokine Receptor-like 3, CKRL3, CKR-L3, CMKBR6, DCR2, DRY6, DRY-6, GPRCY4, GPR-CY4, G-protein Coupled Receptor 29, GPR29, LARC Receptor, STRL22) |
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