Anti -CCR6 (Chemokine (C-C motif) Receptor 6, C-C Chemokine Receptor Type 6, C-C CKR-6,
CC-CKR-6, CCR-6, CKR6, BN-1, CD196, Chemokine Receptor-like 3, CKRL3, CKR-L3, CMKBR6,
DCR2, DRY6, DRY-6, GPRCY4, GPR-CY4, G-protein Coupled Receptor 29, GPR29, LARC Receptor
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
B IH |
|
| CCR6, also termed CKRL3, encodes a 369aa polypeptide with greatest similarity to the family of alpha-chemokine-binding receptors. Unlike most chemokine receptor genes, it is encoded by more than 1 exon. Weakly expressed as a 4kb transcript in spleen, lymph nodes, peripheral blood lymphocytes and appendix, CCR6 gene is located at 6q27. As the receptor for MIP-3-alpha, its activation leads to phospholipase C-dependent intracellular Ca(2+) mobilization. Additionally, CCR6 are markedly upregulated in psoriasis. | | | Catalog # | C2099-70F | | Applications | Suitable for use in Western Blot and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Western Blot: 0.75ug/ml | | Immunohistochemistry (Paraffin): 0.5-1ug/ml; Antigen retrieval with heat is recommended. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | Lyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~0.5mg/ml | | Form | Supplied as a lyophilized powder from PBS, pH 7.4, 5% BSA, 0.05% thimerosal, 0.05% sodium azide. Reconstitute with 200ul sterile ddH2O. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to a sequence at the N-terminal of | | human CCR6. Species Sequence Homology | Rat, mouse (100%). | | Specificity | Recognizes human CCR6. Species Crossreactivity: rat. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
|
|
Questions or comments about this product? Inquire here. |
|
|
Download Specifications for Anti -CCR6 (Chemokine (C-C motif) Receptor 6, C-C Chemokine Receptor Type 6, C-C CKR-6, CC-CKR-6, CCR-6, CKR6, BN-1, CD196, Chemokine Receptor-like 3, CKRL3, CKR-L3, CMKBR6, DCR2, DRY6, DRY-6, GPRCY4, GPR-CY4, G-protein Coupled Receptor 29, GPR29, LARC Receptor |
External Links
|
