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You are here:Home » Antibodies » Abs to G Protein Receptors » Anti -CCR6 (Chemokine (C-C motif) Receptor 6, C-C Chemokine Receptor Type 6, C-C CKR-6, CC-CKR-6, CCR-6, CKR6, BN-1, CD196, Chemokine Receptor-like 3, CKRL3, CKR-L3, CMKBR6, DCR2, DRY6, DRY-6, GPRCY4, GPR-CY4, G-protein Coupled Receptor 29, GPR29, LARC Receptor

Anti -CCR6 (Chemokine (C-C motif) Receptor 6, C-C Chemokine Receptor Type 6, C-C CKR-6,
CC-CKR-6, CCR-6, CKR6, BN-1, CD196, Chemokine Receptor-like 3, CKRL3, CKR-L3, CMKBR6,
DCR2, DRY6, DRY-6, GPRCY4, GPR-CY4, G-protein Coupled Receptor 29, GPR29, LARC Receptor

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B IH
CCR6, also termed CKRL3, encodes a 369aa polypeptide with greatest similarity to the family of alpha-chemokine-binding receptors. Unlike most chemokine receptor genes, it is encoded by more than 1 exon. Weakly expressed as a 4kb transcript in spleen, lymph nodes, peripheral blood lymphocytes and appendix, CCR6 gene is located at 6q27. As the receptor for MIP-3-alpha, its activation leads to phospholipase C-dependent intracellular Ca(2+) mobilization. Additionally, CCR6 are markedly upregulated in psoriasis.
Catalog #C2099-70F
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 0.75ug/ml
Immunohistochemistry (Paraffin): 0.5-1ug/ml; Antigen retrieval with heat is recommended.
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile dH2O. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a lyophilized powder from PBS, pH 7.4, 5% BSA, 0.05% thimerosal, 0.05% sodium azide. Reconstitute with 200ul sterile ddH2O.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to a sequence at the N-terminal of
human CCR6. Species Sequence HomologyRat, mouse (100%).
SpecificityRecognizes human CCR6. Species Crossreactivity: rat.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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