Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to G Proteins » Anti -CCR7 (Chemokine Receptor 7, CC-CCR-7)

Anti -CCR7 (Chemokine Receptor 7, CC-CCR-7)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH IC
CCR7 is a member of the G protein-coupled receptor family (subfamily: chemokine). This receptor was identified as a gene induced by the Epstein-Barr virus (EBV), and is thought to be a mediator of EBV effects on B lymphocytes. CCR7 has been reported to be expressed in blood, bone marrow, lymph node, and intestine. It is particularly expressed in lymphoid tissues and in activated B and T lymphocytes and has been shown to control the migration of memory T cells to inflamed tissues, as well as stimulate dendritic cell maturation. The chemokine (C-C motif) ligand 19 (CCL19/ECL) has been reported to be a specific ligand of this receptor. ESTs have been isolated from blood, embryo, lymph node, and thymus libraries.
Catalog #C2099-71
ApplicationsSuitable for use in Western Blot, ELISA, Immunohistochemistry (Formalin-fixed paraffin-embedded sections) and Immunocytochemistry. Other applications not tested.
Recommended DilutionWesten Blot: 1:1000
ELISA: 1:100,000
Immunohistochemistry (Paraffin): 1:250
Immunocytochemistry: 1:500
Optimal dilutions to be determined by the researcher.
Positive ControlIHC (P): Mouse spleen, human spleen
Western Blot: Cells transfected with CCR7 receptor.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceMouse
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 1mg/ml BSA, 0.1% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide (DPGKPRKNVLVVALLVIFQVC) corresponding to aa2-22 of mouse CCR7. Peptide Sequence Homology
SpecificityRecognizes mouse CCR7. Species Crossreactivity: Human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links