Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to G Protein Receptors » Anti -CCR7 (C-C Chemokine Receptor Type 7, C-C CKR-7, CC-CKR-7, CCR-7, BLR2, CDw197, Epstein-Barr Virus-induced G-protein Coupled Receptor 1, EBI1, EBV-induced G-protein Coupled Receptor 1, MIP-3 beta Receptor, CD197, CMKBR7, EBI1, EVI1)

Anti -CCR7 (C-C Chemokine Receptor Type 7, C-C CKR-7, CC-CKR-7, CCR-7, BLR2, CDw197,
Epstein-Barr Virus-induced G-protein Coupled Receptor 1, EBI1, EBV-induced G-protein
Coupled Receptor 1, MIP-3 beta Receptor, CD197, CMKBR7, EBI1, EVI1)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified IH FC
CCR7 is a chemokine receptor that binds CCL19 and CCL21. CCR7 and its ligands link innate and adaptive immunity through their effects on interactions between T cells and dendritic cells. Naive T cells enter the lymph node through high endothelial venules, which express CCL21. Dendritic cells and macrophages enter the lymph node through afferent lymphatics. The encounter of T cells and dendritic cells in the T cell zone is CCR7-dependent. In addition, during immunological surveillance, B lymphocytes re-circulate between B-cell-rich compartments (follicles or B zones) in secondary lymphoid organs, surveying for antigen. After antigen binding, B cells move to the boundary of B and T zones to interact with T-helper cells; this B cell migration is directed by CCR7 and its ligands. CCR7-positive cancer cell expression has been associated to lymph node metastasis.
Catalog #C2099-71N
ApplicationsSuitable for use in Flow Cytometry and Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 20ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1,k
Clone NoCCR7.6B3
HostMouse
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 150mM sodium chloride, 0.09% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenHuman CCR7
SpecificityRecognizes human CCR7.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


External Links