Anti -CCR8 (C-C Chemokine Receptor Type 8, Chemokine (C-C Motif) Receptor 8, C-C CKR-8,
CC-CKR-8, CCR-8, CC Chemokine Receptor CHEMR1, CDw198, CMKBR8, CMKBRL2, Chemokine
Receptor-like 1, CKRL1, CKR-L1, CY6, GPRCY6, GPR-CY6, MGC129966, MGC129973, TER1)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
IH |
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| CCR8, a Chemokine Receptor, binds the CC-chemokine I-309, which is secreted by umbilical vein endothelial cells. CCR8 also binds viral monocyte inflammatory protein-I (vMIP-I), which is induced by Kaposi sarcoma-related Human herpesvirus-8. CCR8 induces endothelial chemotaxis and may function as an HIV-1 co-receptor on primary Human cells, contributing to HIV-1-induced thymic pathogenesis (Lee et al., 2000). CCR8 expression has been reported in spleen and thymus, natural-killer cells, monocytes, and T cells, and at lower levels in peripheral blood leukocytes. Increased expression has been seen in allergen-challenged atopic asthma. No CCR8 expression was found in mesangial cells of the kidney cortex. ESTs have been isolated from Human normal kidney, eye, and B cell/lung/testis libraries and from Human brain, germ cell, and pancreas cancer libraries. | | | Catalog # | C2099-72T | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (paraffin): 22ug/ml | | Optimal dilutions to be determined by the researcher. | | Positive Control | Human Tonsil, Germinal Center | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.7, 0.1% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to the C-terminal domain of human CCR8. | | Specificity | Recognizes human CCR8. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -CCR8 (C-C Chemokine Receptor Type 8, Chemokine (C-C Motif) Receptor 8, C-C CKR-8, CC-CKR-8, CCR-8, CC Chemokine Receptor CHEMR1, CDw198, CMKBR8, CMKBRL2, Chemokine Receptor-like 1, CKRL1, CKR-L1, CY6, GPRCY6, GPR-CY6, MGC129966, MGC129973, TER1) |
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