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You are here:Home » Antibodies » Abs to G Protein Receptors » Anti -CCR9, Low Endotoxin (C-C chemokine receptor type 9, CC-CKR-9, C-C CKR-9, CCR-9, CDw199, GPR28, GPR-9-6, G-protein coupled receptor 28)

Anti -CCR9, Low Endotoxin (C-C chemokine receptor type 9, CC-CKR-9, C-C CKR-9, CCR-9,
CDw199, GPR28, GPR-9-6, G-protein coupled receptor 28)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified FC
CCR9 is a seven transmembrane protein which is a member of the beta chemokines receptor family. CCR9 is expressed in thymus and small intestine, and mediates the recruitment and development of thymocytes in response to CCL25; the only known ligand of CCR9. CCR9 is an alternative co­receptor with CD4 for HIV infection, and has been implicated in adult T cell leukaemia. Two alternatively spliced transcript variants have been described. Clone 9B1 blocks CCL25­induced Ca2+ release, attenuating inflammation in a murine model of chronic ileitis
when given in early disease stages. CCR9 is an alternative co-receptor with CD4 for HIV infection, and has been implicated in adult T cell leukaemia. Two alternatively spliced transcript variants have been described. Clone 9B1 blocks CCL25-induced Ca2+ release, attenuating inflammation in a murine model of chronic ileitis when given in early disease stages.
Catalog #C2099-73C
ApplicationsSuitable for use in Flow Cytometry and Functional Assays. Other applications not tested.
Recommended DilutionFlow Cytometry: 1:25-1:200; 10ul labels 10e6 cells in 100ul
Optimal dilutions to be determined by the researcher.
HybridomaSpleen cells from immunized Lewis rat were fused with cells of the X63­ Ag8.653 myeloma cell line.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG2a
Clone No9i86
HostRat
SourceMouse
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH7.4. No preservative added.
PurityPurified by Protein G affinity chromatography.
ImmunogenSynthetic peptide corresponding to 25 aa from the amino terminal of murine CCR9 (KLH).
SpecificityRecognizes mouse CCR9.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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