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You are here:Home » Antibodies » Abs to G Protein Receptors » Anti -CCR7 (C-C chemokine receptor type 7, CC-CKR-7, C-C CKR-7, CCR-7, CD197, CDw197, CMKBR7, EBI1, EBV-induced G-protein coupled receptor 1)

Anti -CCR7 (C-C chemokine receptor type 7, CC-CKR-7, C-C CKR-7, CCR-7, CD197, CDw197,
CMKBR7, EBI1, EBV-induced G-protein coupled receptor 1)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rabbit Supernatant B FC
CCR7, or C-C chemokine receptor type 7, is a G protein-coupled, seven-transmembrane domain receptor protein. Originally identified as the EBV-induced gene-1 (1), CCR7 was later found to be the receptor for the chemokines CCL21 (SLC, 6Ckine, Exodus-2) (3) and CCL19 (MIP-3ß, Exodus-3, ELC) (4). CCR7 is expressed in lymphoid tissues and activated B and T lymphocytes (2). It is up-regulated in B cells infected with Epstein-Barr virus and T cells infected with Herpes virus 6 or 7 (4).
Catalog #C2099-73H
ApplicationsSuitable for use in Flow Cytometry, Western Blot. Other applications not tested.
Recommended DilutionFlow Cytometry: 1:20
Western Blotting: 1:500
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Freeze at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
IsotypeIgG
Clone No6k89
HostRabbit
SourceHuman
FormSupplied as a liquid
PuritySupernatant
ImmunogenA synthetic peptide corresponding to residues in loop-3 extracellular domain of human C-C chemokine receptor type 7
SpecificityRecognizes human CCR7 at ~45kD. Does not recognize other CKR family members. Species crossreactivity
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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