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You are here:Home » Antibodies » Abs to G Protein Receptors » Anti -CCR7 (C-C chemokine receptor type 7, CC-CKR-7, C-C CKR-7, CCR-7, CD197, CDw197, CMKBR7, EBI1, EBV-induced G-protein coupled receptor 1)

Anti -CCR7 (C-C chemokine receptor type 7, CC-CKR-7, C-C CKR-7, CCR-7, CD197, CDw197,
CMKBR7, EBI1, EBV-induced G-protein coupled receptor 1)


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Clone Host Grade Applications
Monoclonal Rabbit Purified B IP IH IC IF
CKR7, or C-C chemokine receptor type 7, is a G protein-coupled, seven-transmembrane domain receptor protein. Originally identified as the EBV-induced gene-1, CKR7 was later found to be the receptor for the chemokines CCL21 (SLC, 6Ckine, Exodus-2) and CCL19 (MIP-3 beta, Exodus-3, ELC). CCR7 is expressed in lymphoid tissues and activated B and T lymphocytes. It is up-regulated in B cells infected with Epstein-Barr virus and T cells infected with herpesvirus 6 or 7.
Catalog #C2099-73K
ApplicationsSuitable for use in Western Blot, Immunoprecipitation, Immunofluorescence/Immunocytochemistry and Immunohistochemistry. Not suitable for use in Flow Cytometry. Other applications not tested.
Recommended DilutionsWestern Blot: 1:5000 detects a band at ~48kD.
Immunohistochemistry: (Paraffin): 1:250
Immunofluorescence (IC): 1:250
Immunoprecipitation: 1:10
Optimal dilutions to be determined by the researcher.
Positive ControlK562 and Daudi cell lysates, human spleen tissue and HeLa cells.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Manufactured incorporating RabMAb® technology under Epitomics US patents, No 5,675,063 and 7,429,487, owned by Abcam.
Clone TypeMonoclonal
Clone No6k91
FormSupplied as a liquid in PBS, 0.05% BSA, 0.01% sodium azide, 50% glycerol
ImmunogenA synthetic peptide corresponding to residues in N-terminal extracellular domain of human CKR7. Cellular Localization: Cell membrane.
SpecificityRecognizes human CKR7. Species Crossreactivity: mouse, rat and Rhesus monkey. Does not recognize other G-protein coupled receptor 1 family members.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

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