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You are here:Home » Antibodies » Abs to G Protein Receptors » Anti -CCR10 (C-C Chemokine Receptor 10, CC-CCR-10, GPR2)

Anti -CCR10 (C-C Chemokine Receptor 10, CC-CCR-10, GPR2)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH IC
Receptors for the C-C chemokine family include CCR-1, CCR-2A, CCR-3, CCR-4, CCR-5 and the Duffy blood group antigen. The C-C receptors are important in the function of T cell chemotaxis and migration of phagocytic cells to sites of inflammation. CCR10 in particular is the receptor for the skin-associated CC chemokine CCL27 (CTACK) as well as the novel chemokine CCL28 which displays chemotactic activity for resting CD4+ and CD8+ T cells.
Catalog #C2099-74K
Cellular Localization Cell Membrane
ApplicationsSuitable for use in ELISA, Western Blot, Immunohistochemistry and Immunocytochemistry. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot Store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostGoat
SourceHuman
ConcentrationAs reported
Form10 mM KHPO4, 140 mM NaCl, pH 7.2.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide: VSWGHYSGDEEDAYSAEPLPELC, corresponding to amino acids 9-31 of Human CCR10.
SpecificityPeptide sequence is < 50% identical to other human chemokine receptors in this region. Species Crossreactivity: Crossreacts with Human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesC-C Chemokine Receptor 10, CC-CCR-10


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