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You are here:Home » Antibodies » Abs to G Proteins » Anti -CCR1 (Chemokine Receptor 1, CC-CKR-1)

Anti -CCR1 (Chemokine Receptor 1, CC-CKR-1)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified E B IH
Chemokine receptors are specialized proteins that function at the surface of cells, and enable chemokines to trigger internal cellular processes. Chemokines and their receptors play a pivotal role in lymphocyte trafficking, recruiting and recirculation. Chemokines act through seven transmembrane G protein-coupled receptors. The chemokine system is increasingly recognized to play an important role in lymphocyte biology.
Catalog #C2099-76
Application(s)ELISA 1:50,000
Western Blotting: 1:1,000. Western Blot on membranes from human peripheral blood leukocytes or human T-cell line Jurkatt.
Immunohistochemistry: 1:300
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostRabbit
SourceHuman
ConcentrationNot determined
FormSupplied as a liquid in PBS, pH 7.4, 1mg/ml BSA, 0.1% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic Peptide TEDYDTTTEFDYGDATPC and corresponds to amino acid residues 7-24 of human C-C Chemokine Receptor 1.
SpecificityPeptide sequence shares less than 50% amino acid identity to other Chemokine receptors in this region. Since the peptide sequence shares less than 50% amino acid identity to other chemokine receptors in this region, this antibody only recognizes human receptor. Crossreacts with human.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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