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You are here:Home » Antibodies » Abs to G Proteins » Anti -CCR2 (Chemokine Receptor 2, CC-CKR-2)

Anti -CCR2 (Chemokine Receptor 2, CC-CKR-2)

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Specifications

Clone Host Grade Applications
Polyclonal Goat Affinity Purified E B IH
Chemokine receptors are specialized proteins that function at the surface of cells, and enable chemokines to trigger internal cellular processes. Chemokines and their receptors play a pivotal role in lymphocyte trafficking, recruiting and recirculation. Chemokines act through seven transmembrane G protein-coupled receptors. The chemokine system is increasingly recognized to play an important role in lymphocyte biology.
Catalog #C2099-80
ApplicationsSuitable for use in ELISA, Western Blot and Immunohistochemistry. Other applications have not been tested.
Recommended DilutionELISA: 1:30,000
Western Blot: 1:500
Immunohistochemistry: 1:100
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
HostGoat
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 1mg/ml BSA, 0.1% sodium azide before the addition of 40% glycerol.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide CGEEVTTFFDYDYGAPCHKFDVKQ corresponding to the N-terminal extracellular domain of human CCR2.
SpecificityRecognizes human CCR2. Species sequence homology: < 50% identical to other chemokine receptors in this region.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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