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Anti -CCR2 (Chemokine receptor 2, CC-CCR-2, CKR2)
Anti -CCR2 (Chemokine receptor 2, CC-CCR-2, CKR2)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Purified |
E |
|
| ELISA positive samples that are still undergoing R&D testing. Available testing data will be listed under the Applications section. Often times, multiple samples will be included, differing in the amino acid sequence used to raise the immune sera. | | | Catalog # | C2099-91A | | Chemokines play important roles in inflammation and critical for the recruitment of effector immune cells to sites of infection. Chemokines activate leukocytes by binding to G protein coupled receptors (1). The ever-growing chemokine receptor subtypes can be divided into 2 major groups, CXCR and CCR, based on the 2 major classes of chemokines. One of the CCR receptors, CCR1, is expressed on neutrophils, monocytes, lymphocytes, and eosinophils and binds the leukocyte chemoattractant and hemopoiesis regulator macrophage-inflammatory protein (MIP-1 ), eotaxin, as well as several other related chemokines (2-4). Mice lacking the chemokine receptor CCR1 have defects in neutrophil trafficking and proliferation (5,6). | | Applications | Suitable for use in ELISA. Other applications have not been tested. | | Recommended Dilution | ELISA: 1:100-1:1000 | | Storage and Stability | May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | As reported | | Form | Supplied as a liquid in glycerol, 0.1% sodium azide. | | Purity | Purified | | Immunogen | Synthetic peptide corresponding to amino acids 352-366 of human CCR2. | | Specificity | Recognizes Human CCR2. | | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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