Login

Forgot your password?
New User?
Remember me
banner banner

You are here:Home » Antibodies » Abs to G Protein Receptors » Anti -CCR3 (CD193, CC Chemokine Receptor Type 3, CC CKR 3, CC CKR3, B Chemokine Receptor, CMKBR3, Eosinophil CC Chemokine Receptor 3, Eosinophil Eotaxin Receptor, MGC102841)

Anti -CCR3 (CD193, CC Chemokine Receptor Type 3, CC CKR 3, CC CKR3, B Chemokine Receptor,
CMKBR3, Eosinophil CC Chemokine Receptor 3, Eosinophil Eotaxin Receptor, MGC102841)

Pricing

  For pricing information, USA customers sign in.
  Outside USA? Please contact your distributor for pricing.

Specifications

Clone Host Grade Applications
Monoclonal Mouse Affinity Purified FC IF
CCR3 is a receptor for CC chemokine eotaxin 1 and eotaxin 2. CCR3 has been reported in blood, brain, lung, bone marrow, kidney, liver, lymph node, placenta, skin, spleen, thymus, thyroid, uterus and vessel. Within these tissues, CCR3 is expressed in specific cell types, including eosinophils, basophils, Th2 cells and mast cells. The agonists for CXCR3 (IP-10, mig, and I-TAC) act as antagonists for CCR3 by competing for the binding of eotaxin to CCR3. The 356 amino acid CCR3 receptor is expressed on human eosinophils, basophils, neutrophils, mast cells, mononuclear phagocytes, platelets, CD34+ hematopoietic progenitor cells, Th2 like lymphocytes and keratinocytes. CCR3 is thought to play a key role in allergic diseases such as bronchial asthma and allergic rhinitis. CCR3 is a co-receptor for HIV 1 and 2 and the binding of eotaxin with CCR3 has been shown to inhibit HIV infection in some cell types. The CCR3 receptor has been reported to be upregulated by high affinity Fc IgE receptor ligation.
Catalog #C2099-92J
ApplicationsSuitable for use in Flow Cytometry and Immunofluorescence. Other applications not tested.
Recommended DilutionOptimal dilutions to be determined by the researcher.
ControlsBlood eosinophils and basophils
Storage and StabilityMay be stored at 4°C. For long-term storage, aliquot and store at 4°C. Do not freeze. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Further dilutions can be made in assay buffer. 
Clone TypeMonoclonal
IsotypeIgG2a
Clone No8J549
HostMouse
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
PurityPurified by affinity chromatography.
ImmunogenHuman CCR3. Cellular Localization: Integral membrane protein
SpecificityRecognizes human CCR3.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesB Chemokine Receptor, C C chemokine receptor type 3, C C CKR 3, CC Chemokine Receptor 3, CC chemokine receptor type 3, CC CKR 3, CC R3, CCCKR3, CCR 3, CD 193, CD193, CD193 antigen, Chemokine (C C motif) receptor 3, Chemokine (CC) Receptor 1 Like 2, Chemok


External Links