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You are here:Home » Antibodies » Antibodies-G Proteins » Anti -CCR4 (CC chemokine receptor type 4, CCCKR4, CCR4, ChemR13, CKR4, CMKBR4, HGCN 14099, K5 5, MGC88293)

Anti -CCR4 (CC chemokine receptor type 4, CCCKR4, CCR4, ChemR13, CKR4, CMKBR4, HGCN 14099,
K5 5, MGC88293)


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Clone Host Grade Applications
Monoclonal Mouse Purified E FC IF
CCR4 (CC chemokine receptor 4) molecule belongs to the rhodopsin family of G-protein coupled receptors. Chemokine receptors are membrane bound molecules composed of 7-transmembrane domains and coupled to G-proteins. CCR4 binds the chemokines CCL17 (TARC) and CCL22 (MDC) and is highly expressed in most single-positive CD4(+) thymocytes especially in TH2- and regulatory T-cells. It plays a central role in T cell migration to the thymus, T cell maturation and education. CCR4 is often up-regulated in inflammation and cause conformational changes that trigger intracellular signaling pathways.
Catalog #C2099-93H
ApplicationsSuitable for use in Immunofluorescence/Immunocytochemistry, Flow Cytometry and ELISA. Other applications not tested.
Recommended DilutionImmunofluorescence (IC): 1ug/10e6 cells
Flow Cytometry: 1.2ug/10e6 cells
ELISA: 1:200-1:400
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
Clone No9E72
FormSupplied as a liquid in PBS, pH 7.2.
ImmunogenHuman CCR4 peptide
SpecificityRecognizes human CCR4. Selection based on recognition of the complete native protein expressed on transfected mammalian cells.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Alternate namesCC chemokine receptor 4

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