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You are here:Home » Antibodies » Abs to G Protein Receptors » Anti -CCR5 (Chemokine (C-C motif) Receptor 5, C-C Chemokine Receptor Type 5, CCCKR5, CC-CKR-5, C-C CKR-5, CCR-5, AM4-7, CD195, CHEMR13, CKR5, CMKBR5, FLJ78003, HIV-1 Fusion Coreceptor, IDDM22)

Anti -CCR5 (Chemokine (C-C motif) Receptor 5, C-C Chemokine Receptor Type 5, CCCKR5,
CC-CKR-5, C-C CKR-5, CCR-5, AM4-7, CD195, CHEMR13, CKR5, CMKBR5, FLJ78003, HIV-1 Fusion
Coreceptor, IDDM22)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Rat Affinity Purified B
CCR5(CC chemokine receptor 5; also CD195 and MIP­1a receptor)is a 41­44kD member of the G­protein coupled receptor #1 family of proteins. It is expressed on Treg cells, NK cells, neurons,macrophages and Th1 cells. CCR5 mediates cell adhesion and migration induced by several chemokines including CCL3/MIP­1a, CCL4/MIP­1b, CCL5/RANTES, and CCL8/MCP­2. It also functions as a coreceptor for macrophage­tropic HIV1 infection. CCR5 contains O­
glycosylated and sulfated extracellular N­terminus (aa1­32), and a phosphorylated and palmitoylated intracellular C­terminus (aa304354). CR5 will form homodimers,heterodimers with CCR2,and heterooligomers with CCR2 and CXCR4. Within aa1­32, mouse CCR5 shares 72% and 91% aa sequence identity with human and rat CCR5, respectively.
Catalog #C2099-99L
ApplicationsSuitable for use in Western Blot. Other applications not tested.
Recommended DilutionWestern Blot: 2mg/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityLyophilized powder may be stored at -20°C. Stable for 12 months at -20°C. Reconstitute with sterile PBS. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Reconstituted product is stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypeMonoclonal
IsotypeIgG
Clone No11D98
HostRat
SourceMouse
ConcentrationNot determined
FormSupplied as a lyophilized powder in PBS with trelahose. Reconstitute with sterile PBS.
PurityPurified by Protein A/G affinity chromatography.
ImmunogenRecombinant corresponding to mouse CCR5 expressed in E. coli (P51682).
SpecificityRecognizes mouse CCR5.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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