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You are here:Home » Antibodies » Abs to G Proteins » Anti -CCR8 (C-C Chemokine Receptor Type 8, C-C CKR-8, CC-CKR-8, CCR-8, CC Chemokine Receptor CHEMR1, CDw198, Chemokine Receptor-like 1, CKRL1, CKR-L1, CMKBR8, CMKBRL2, CY6, GPRCY6, GPR-CY6, TER1)

Anti -CCR8 (C-C Chemokine Receptor Type 8, C-C CKR-8, CC-CKR-8, CCR-8, CC Chemokine
Receptor CHEMR1, CDw198, Chemokine Receptor-like 1, CKRL1, CKR-L1, CMKBR8, CMKBRL2, CY6,
GPRCY6, GPR-CY6, TER1)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
CCR8 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human and murine CCR8 were cloned and designated TER1, CKR-L1, and ChemR1. The encoded seven transmembrane protein was identified as the receptor for human CC chemokine I-309 and renamed CCR8. Recently, CCR8 was found to serve as a coreceptor for diverse T-cell tropic, dual-tropic and macrophage-tropic HIV-1 strains. CCR8 mediates CC chemokine I-309 induced monocyte chemoattraction and HIV-1 envelope fusion and virus infection, which can be prevented by the CCR8 ligand I-309. CCR8 is expressed in spleen, thymus and T lymphoblastic cell lines.
Catalog #C2100-02F
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml
Optimal dilutions to be determined by the researcher.
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, 0.1% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to 3rd cytoplasmic domain of human CCR8 (KLH).
SpecificityRecognizes human C-C Chemokine Receptor 8. Species sequence homology: Mouse (57/84%).
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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