Anti -CCR8 (C-C Chemokine Receptor Type 8, C-C CKR-8, CC-CKR-8, CCR-8, CC Chemokine
Receptor CHEMR1, CDw198, Chemokine Receptor-like 1, CKRL1, CKR-L1, CMKBR8, CMKBRL2, CY6,
GPRCY6, GPR-CY6, TER1)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Polyclonal |
Rabbit |
Affinity Purified |
IH |
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| CCR8 is one of the chemokine receptors that are required as coreceptors for HIV infection. The genes encoding human and murine CCR8 were cloned and designated TER1, CKR-L1, and ChemR1. The encoded seven transmembrane protein was identified as the receptor for human CC chemokine I-309 and renamed CCR8. Recently, CCR8 was found to serve as a coreceptor for diverse T-cell tropic, dual-tropic and macrophage-tropic HIV-1 strains. CCR8 mediates CC chemokine I-309 induced monocyte chemoattraction and HIV-1 envelope fusion and virus infection, which can be prevented by the CCR8 ligand I-309. CCR8 is expressed in spleen, thymus and T lymphoblastic cell lines. | | | Catalog # | C2100-02F | | Applications | Suitable for use in Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry (Formalin fixed paraffin embedded): 5ug/ml | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Polyclonal | | Isotype | IgG | | Host | Rabbit | | Source | Human | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, 0.1% sodium azide. | | Purity | Purified by immunoaffinity chromatography. | | Immunogen | Synthetic peptide corresponding to 3rd cytoplasmic domain of human CCR8 (KLH). | | Specificity | Recognizes human C-C Chemokine Receptor 8. Species sequence homology: Mouse (57/84%). | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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Download Specifications for Anti -CCR8 (C-C Chemokine Receptor Type 8, C-C CKR-8, CC-CKR-8, CCR-8, CC Chemokine Receptor CHEMR1, CDw198, Chemokine Receptor-like 1, CKRL1, CKR-L1, CMKBR8, CMKBRL2, CY6, GPRCY6, GPR-CY6, TER1) |
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