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You are here:Home » Antibodies » Abs to G Protein Receptors » Anti -CCR10 (C-C Chemokine Receptor Type 10, Chemokine (C-C Motif) Receptor 10, C-C CKR-10, CC-CKR-10, CCR-10, G-protein Coupled Receptor 2, GPR2)

Anti -CCR10 (C-C Chemokine Receptor Type 10, Chemokine (C-C Motif) Receptor 10, C-C
CKR-10, CC-CKR-10, CCR-10, G-protein Coupled Receptor 2, GPR2)

Pricing

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified IH
GPR2/CCR10, a Chemokine Receptor, encodes a protein that most closely resembles the interleukin-8 receptor. The keratinocyte-produced chemokine CCL27 activates CCR10 and is involved in T cell-mediated skin inflammation. GRP2/CCR10 has been reported to be ubiquitously expressed. Transcripts for this receptor have been identified in peripheral tissues including adult small intestine and fetal liver, testis, placenta, and skin. In the skin, this receptor is constitutively expressed in melanocytes, fibroblasts, and microvascular endothelial cells. It is also detected in T cells, Langerhans cells, and peripheral blood mononuclear cells but not in keratinocytes (Homey et al., 2000), dendritic cells, or in various brain regions (Marchese et al., 1994). ESTs have been isolated from brain, eye, and kidney libraries.
Catalog #C2100-15C
ApplicationsSuitable for use in Immunohistochemistry. Other applications not tested.
Recommended DilutionImmunohistochemistry (paraffin): 3-4ug/ml
Optimal dilutions to be determined by the researcher.
Positive ControlHuman Tonsil
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~1mg/ml
FormSupplied as a liquid in PBS, pH 7.7, 0.1% sodium azide.
PurityPurified by immunoaffinity chromatography.
ImmunogenSynthetic peptide corresponding to the C-terminal domain of human G Protein-Coupled Receptor CCR10.
SpecificityRecognizes human CCR10.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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