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You are here:Home » Antibodies » Abs to G Protein Receptors » Anti -CCR10 (CC Chemokine receptor 10, CC-CCR-10, G protein-coupled receptor 2, GRP2)

Anti -CCR10 (CC Chemokine receptor 10, CC-CCR-10, G protein-coupled receptor 2, GRP2)

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Specifications

Clone Host Grade Applications
Polyclonal Rabbit Affinity Purified B
Recently, a function has been assigned to a previously identified orphan chemokine receptor, GPR-2. This receptor, also called CCR10, binds with monocyte chemoattractant protein (MCP)-1, MCP-3 and MIP-1 beta. CCR10 is expressed by melanocytes, dermal fibroblasts, dermal microvascular endothelial cells, T cells as well as in skin-derived Langerhans cells. CCR10 may play a role in both skin homeostasis as well as a potential role in inflammatory responses.
Catalog #C2102
ApplicationsSuitable for use Flow Cytometry, Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1-2ug/ml In A-375, ~50kD band is observed.
Optimal dilutions to be determined by the researcher.
Positive Control A-375 or MCF-7
Storage and StabilityMay be stored at 4°C for short-term only. For long-term storage and to avoid repeated freezing and thawing, aliquot and add glycerol (40-50%). Freeze at -20°C. Aliquots are stable for 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer.
Clone TypePolyclonal
IsotypeIgG
HostRabbit
SourceHuman
Concentration~0.5mg/ml
FormSupplied as a liquid in PBS, pH 7.2, 0.05% sodium azide, 0.2% gelatin.
PurityPurified by Protein G affinity chromatography.
ImmunogenPeptide corresponding to amino acids 350-362 of human CCR10.
SpecificityRecognizes CCR10. Species Crossreactivity: Human. Predicted to crossreact with mouse. In this region, mouse and human amino acid sequences are 100% identical.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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