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Anti -CD8 (Leu2 T lymphocyte antigen, MAL, OKT8 T Cell antigen, p32, T cell antigen Leu2, T cell surface glycoprotein CD8 alpha, Suppressor/Cytotoxic T cell)
Anti -CD8 (Leu2 T lymphocyte antigen, MAL, OKT8 T Cell antigen, p32, T cell antigen Leu2,
T cell surface glycoprotein CD8 alpha, Suppressor/Cytotoxic T cell)
Pricing
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| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
IH |
|
| The CD8 complex interacts with class I MHC molecules resulting in increased adhesion between CD8+ T-lymphocytes and their target cells. Binding of the CD8 antigen to Class I MHC molecules enhances T-cell activation (3). The cytoplasmic portion of the CD8 antigen is associated with a protein tyrosine kinase (p561ck)(4). | | | Catalog # | C2259-36 | | Applications | Suitable for use in Immunohistochemistry. Other applications have not been tested. | | Recommended Dilutions | Immunohistochemistry: Frozen tissue and formalin-fixed paraffin embedded tissue sections. | | Optimal dilutions to be determined by the researcher. | | Storage and Stability | May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. | | CAS Number | n/a | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 2Q1751 | | Host | Mouse | | Source | Rat | | Concentration | ~1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.2, 10mM sodium azide. | | Purity | Purified by Protein A affinity chromatography | | Immunogen | Rat thymocyte membrane glycoproteins. | | Specificity | Recognizes rat CD8 alpha antigen present on a subset of T-cells that has suppressor and cytotoxic activities. 90% of thymocytes and NK cells are labelled with CD8. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
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