Anti -CD10 (CALLA, Common Acute Lymphocytic Leukemia Antigen, Neprilysin, NEP, Neutral
Endopeptidase 24.11, EC3.4.24.11)
Pricing
For pricing information, USA customers sign in. Outside USA? Please contact your distributor for pricing. Specifications
| Clone |
Host |
Grade |
Applications |
| Monoclonal |
Mouse |
Affinity Purified |
IH FC IF |
|
| CD10 (CALLA, Common Acute Lymphocytic Leukemia Antigen, Neprilysin, NEP, Neutral Endopeptidase 24.11, EC3.4.24.11) is a single chain 100kD glycoprotein. It is a cell surface enzyme with neutral metalloendopeptidase activity which inactivates a variety of biologically active peptides. CD10 is expressed on the cells of lymphoblastic, Burkitt’s, and follicular germinal center lymphomas, and on cells from patients with chronic myelocytic leukemia (CML). It is also expressed on the surface of normal early lymphoid progenitor cells, immature B cells within adult bone marrow and germinal center B cells within lymphoid tissue. CD10 is also present on breast myoepithelial cells, bile canaliculi, fibroblasts, with especially high expression on the brush border of kidney and gut epithelial cells. | | | Antigen Distribution: Granulocytes > 95%; cALL > 95%; Peripheral blood lymphocytes < 1%; T cells (lg+) < 1%; B cells (lg-) < 1%; Monocytes < 1%; Thymocytes < 1%; NK cells (CD16+) < 1%. | | | Catalog # | C2261-49 | | Applications | Suitable for use in Immunofluorescence, Flow Cytometry and Immunohistochemistry. Other applications not tested. | | Recommended Dilution | Immunohistochemistry: Acetone-fixed frozen | | Optimal dilutions to be determined by the researcher. | | Positive Control | Tonsil or small intestine | | Storage and Stability May be stored at 4°C for short-term only. For long-term storage, store at -20°C. Aliquots are stable for at least 12 months at -20°C. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap. Further dilutions can be made in assay buffer. | | Clone Type | Monoclonal | | Isotype | IgG1 | | Clone No | 0.N.70 | | Host | Mouse | | Source | Human | | Concentration | ~0.1mg/ml | | Form | Supplied as a liquid in PBS, pH 7.4, 0.2% BSA, 0.09% sodium azide, before the addiion of glycerol to 40%. Also available without BSA and sodium azide. See C2261-49X. | | Purity | Purified by Protein G affinity chromatography. | | Immunogen | Raji cells. Cellular Localization: Cell membrane | | Specificity | Recognizes human CD10 at 100kD. | | | Important Note | This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological. |
External Links
|
