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You are here:Home » Antibodies » Abs to CD Markers » Anti -CD10 (Neprilysin, Atriopeptidase, Common Acute Lymphocytic Leukemia Antigen, CALLA, Enkephalinase, Neutral Endopeptidase 24.11, NEP, Neutral Endopeptidase, Skin Fibroblast Elastasem, SFE, MME, EPN)

Anti -CD10 (Neprilysin, Atriopeptidase, Common Acute Lymphocytic Leukemia Antigen, CALLA,
Enkephalinase, Neutral Endopeptidase 24.11, NEP, Neutral Endopeptidase, Skin Fibroblast
Elastasem, SFE, MME, EPN)

Pricing

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Specifications

Clone Host Grade Applications
Monoclonal Mouse Supernatant B IH
CD10 is a 90-110kD cell surface glycoprotein expressed on normal early lymphoid progenitor cells, immature B-cells in adult bone marrow and mature germinal center B cells in lymphoid tissue. It is also expressed in some non-lymphoid tissues such as fibroblasts, breast myoepithelium, gut epithelial cells and brush border of Kidney. CD10 is a zinc-binding enzyme with a neutral metalloendopeptidase activity which inactivates a range of biologically active peptides. It is a tumor-specific antigen expressed on cells of lymphoblastic, Burkitt's and follicular germinal center lymphoma and on cells from patients with CML. CD10 has been used as a positive immunohistochemical marker in the diagnosis of human ALL and renal cell carcinomas.
Catalog #C2261-50B
ApplicationsSuitable for use in Western Blot and Immunohistochemistry. Other applications not tested.
Recommended DilutionWestern Blot: 1:1000
Immunohistochemistry (formalin fixed paraffin embedded): 1:20-1:30
Immunohistochemistry: Frozen
Optimal dilutions to be determined by the researcher.
Positive ControlTonsil
Storage and StabilityMay be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for at least 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Clone TypeMonoclonal
IsotypeIgG1
Clone No11E68
HostMouse
SourceHuman
ConcentrationNot determined.
FormSupplied as a liquid, 0.05% sodium azide.
PuritySupernatant
ImmunogenProkaryotic recombinant corresponding to the external domain of the CD10 glycoprotein. Cellular Localization: Cell membrane.
SpecificityRecognizes human CD10.
Important NoteThis product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.


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